Novel Immuno-oncology Biomarker Testing Market Report

Demand for novel immuno-oncology biomarker testing is foreseen to show growth on the back of the rising need for high success rates of cancer treatments and clinical cancer researches. There are various anti-cancer vaccines, immunotherapies, and targeted therapies available for cancer treatment. However, physicians and researchers have grappled with major obstacles such as treatment-based adverse effects and drug-related limitations. This where the role of multiple novel biomarkers comes into play. Today, scientists are able to identify advanced cancer biomarkers with the help of biotechnological advancement.

Cancer Research Initiatives to Work in Favor of Global Market

Increasing investigation of mismatch repair deficiency, microsatellite instability, tumor mutation burden, and other novel cancer biomarkers is predicted to highlight the global novel immuno-oncology biomarker testing market. Rising number of clinical research initiatives for studying the application and relevance of several novel cancer biomarkers could augur well for the global market. Need to make personalized cancer treatment-related decisions is encouraging the development of analytical tests for cancer biomarkers.

Oncology Testing and Service Deals to Give Strength to Product Portfolio

Some of the leading players of the global novel immuno-oncology biomarker testing market are Agilent Technologies, Inc., Biodesix, Eli Lilly and Company, AstraZeneca, Ventana Medical Systems, Inc., Genentech Inc., Bristol-Myers Squibb, Merck & Co., Inc., and Pfizer Inc. Besides collaboration, acquisition is a powerful strategy that could help players to gain a significant share of the global market. In July 2019, Interpace Diagnostics Group, a US provider of clinically useful molecular and related first-line diagnostic tests for evaluating cancer risk, signed the acquisition of the biopharma services business of Cancer Genetics, Inc., a US DNA-based cancer diagnostics company.

By Testing Method

●   Tumor Infiltrating Lymphocytes (TILs)

●   Microsatellite Instability

●   Tumor Mutational Burden

●   Others

By Application

●   Blood Cancer

●   Colon Cancer

●   Prostate Cancer

●   Colorectal Cancer

●   Melanoma

●   Lung Cancer

●   Others

By Technology Type

●   Immunohistochemistry

●   Next-generation Sequencing

●   Polymerase Chain Reaction

●   Others

By End Use

●   Research Use

●   Clinical Use

●   Commercial Use

The market share of research use is expected to increase in future as growing number of immuno-oncology and cancer diagnostics companies continue to partner with each other. In July 2019, Immodulon Therapeutics Ltd., a UK-based clinical-stage immuno-oncology company, and Biodesix Inc., a US molecular diagnostics company, formed a biomarker research partnership focusing on pancreatic cancer treatment.

Immunohistochemistry is a popular technology used in the global novel immuno-oncology biomarker testing market. In July 2019, a top-performing series of immunohistochemistry antibodies called PathPlus was released by LifeSpan BioSciences, Inc., a US provider of enzyme-linked immunosorbent assay kits, biochemicals, proteins, and antibodies. These antibodies will be used to detect 200 high-value cancer targets.

TILs are increasingly adopted in cancer therapy research and development mainly because of the versatility and potential of T cells. In May 2019, Iovance Biotherapeutics, Inc., a US developer of novel cancer immunotherapies based on TILs, announced an objective response rate of 44% in advanced cervical cancer patients treated with TIL therapy LN-145. The company also announced an objective response rate of 38% in advanced melanoma patients treated with TIL therapy lifileucel.

By Region

High number of collaborations and partnerships focusing on the development of effective oncology treatments is anticipated to push the demand in the North America novel immuno-oncology biomarker testing market. In July 2019, Freenome, a US AI genomics biotech company, closed its Series B financing of $160 million to help advance its multi-omics blood testing platform for early cancer detection.

Increasing research on blood cancer treatments is expected to draw the attention to novel immuno-oncology biomarker testing in North America. In July 2019, the UNC Lineberger Comprehensive Cancer Center, a US cancer research and treatment center, developed an experimental therapeutic compound to block a hyperactive cell signal contributing to tumor growth in primary effusion lymphoma, a type of blood cancer.

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